Glycine

The simplest alpha-amino acid and the achiral exception among common protein amino acids.

Formula
C2H5NO2
Functional group
Amino acids
Molar mass
75.07 g/mol
Also known as
2-aminoacetic acid, aminoacetic acid, Aminoethanoic acid, Glycocoll, Glycolixir, Glicoamin

Overview

The simplest alpha-amino acid and the achiral exception among common protein amino acids.

Its side chain is hydrogen, leaving two identical hydrogens on the alpha carbon. The amino and carboxyl groups give pH-dependent charge states, commonly represented by a zwitterion. Glycine therefore connects acid–base equilibria with the structural requirements for optical isomerism.

Identifiers

Formula
C2H5NO2
Functional group
Amino acids
Molar mass
75.07 g/mol
Also known as
2-aminoacetic acid, aminoacetic acid, Aminoethanoic acid, Glycocoll, Glycolixir, Glicoamin
Chemical identifiers
SMILES
C(C(=O)O)N
InChI
InChI=1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)
PubChem CID
750

Properties

Melting / decomposition
290 °C decomposes
Density
1.161 g/cu cm @ 20 °C
Water solubility
water solubility = 2.49X10+5 mg/l @ 25 °C
Data availability

Not published: Boiling Point.

Related compounds

References

  1. PubChem Compound Summary: Glycine (CID 750)National Center for Biotechnology Information · PubChem

    Identity, molecular formula, molecular weight and aliases retrieved via PUG REST on 2026-09-08.

  2. OpenStax Organic Chemistry: Structures of amino acidsJohn McMurry · OpenStax · 2023

    Supports the qualitative structural interpretation of the recorded molecular structure; no new physical measurement or verified preparative yield is claimed.

  3. Hazardous Substances Data Bank (HSDB): Glycine — melting pointHazardous Substances Data Bank (HSDB)

    Retrieved through PubChem PUG View on 2026-09-08. https://pubchem.ncbi.nlm.nih.gov/compound/750#section=Melting-Point. Source value, complete property clause or compact miscibility statement retained; absent pressure, temperature or phase conditions are not inferred. Original reference: Lide, D.R. (ed.). CRC Handbook of Chemistry and Physics. 79th ed. Boca Raton, FL: CRC Press Inc., 1998-1999., p. 3-173

  4. Hazardous Substances Data Bank (HSDB): Glycine — densityHazardous Substances Data Bank (HSDB)

    Retrieved through PubChem PUG View on 2026-09-08. https://pubchem.ncbi.nlm.nih.gov/compound/750#section=Density. Source value, complete property clause or compact miscibility statement retained; absent pressure, temperature or phase conditions are not inferred. Original reference: Lide, D.R. (ed.). CRC Handbook of Chemistry and Physics. 79th ed. Boca Raton, FL: CRC Press Inc., 1998-1999., p. 3-173

  5. Hazardous Substances Data Bank (HSDB): Glycine — solubilityHazardous Substances Data Bank (HSDB)

    Retrieved through PubChem PUG View on 2026-09-08. https://pubchem.ncbi.nlm.nih.gov/compound/750#section=Solubility. Source value, complete property clause or compact miscibility statement retained; absent pressure, temperature or phase conditions are not inferred. Original reference: Yalkowsky SH, Dannenfelser RM; The AQUASOL dATAbASE of Aqueous Solubility. Fifth Ed, Tucson, AZ: Univ Az, College of Pharmacy (1992)