Hexamethylenediamine

The diamine paired with adipic acid to make nylon 6,6.

Formula
C6H16N2
Functional group
Two amine groups
Molar mass
116.2 g/mol
Also known as
hexane-1,6-diamine, HMDA, HMD

Overview

Hexane-1,6-diamine

The diamine paired with adipic acid to make nylon 6,6.

Its two amine groups react with acid groups to form amide links. Industrial preparation commonly starts from a balanced nylon salt made with adipic acid.

Identifiers

Formula
C6H16N2
Functional group
Two amine groups
Molar mass
116.2 g/mol
Also known as
hexane-1,6-diamine, HMDA, HMD
Chemical identifiers
SMILES
NCCCCCCN
InChI
InChI=1S/C6H16N2/c7-5-3-1-2-4-6-8/h1-8H2
PubChem CID
16402

Properties

Melting Point
42 °C
Boiling Point
205 °C
Relative density (water = 1)
Relative density (water = 1): 0.93
Water solubility
Water solubility = 2,460,000 mg/l at 4.5 °C

Related compounds

  • Diamines

    The diamine paired with adipic acid to make nylon 6,6.

References

  1. PA 6 and PA 66 intermediatesBASF
  2. Reference document on best available techniques in the production of polymersEuropean Commission, Joint Research Centre · 2007
  3. PubChem: HexamethylenediamineNational Center for Biotechnology Information

    Identity retrieved 2026-09-08; matched against the record's isomeric structure. Unspecified stereochemistry remains unspecified.

  4. Hazardous Substances Data Bank (HSDB): Hexamethylenediamine — melting pointHazardous Substances Data Bank (HSDB)

    Retrieved through PubChem PUG View on 2026-09-08. https://pubchem.ncbi.nlm.nih.gov/compound/16402#section=Melting-Point. Source value, complete property clause or compact miscibility statement retained; absent pressure, temperature or phase conditions are not inferred. Original reference: Budavari, S. (ed.). The Merck Index - An Encyclopedia of Chemicals, Drugs, and Biologicals. Whitehouse Station, NJ: Merck and Co., Inc., 1996., p. 802

  5. Hazardous Substances Data Bank (HSDB): Hexamethylenediamine — boiling pointHazardous Substances Data Bank (HSDB)

    Retrieved through PubChem PUG View on 2026-09-08. https://pubchem.ncbi.nlm.nih.gov/compound/16402#section=Boiling-Point. Source value, complete property clause or compact miscibility statement retained; absent pressure, temperature or phase conditions are not inferred. Original reference: Budavari, S. (ed.). The Merck Index - An Encyclopedia of Chemicals, Drugs, and Biologicals. Whitehouse Station, NJ: Merck and Co., Inc., 1996., p. 802

  6. ILO-WHO International Chemical Safety Cards (ICSCs): Hexamethylenediamine — densityILO-WHO International Chemical Safety Cards (ICSCs)

    Retrieved through PubChem PUG View on 2026-09-08. https://pubchem.ncbi.nlm.nih.gov/compound/16402#section=Density. Source value, complete property clause or compact miscibility statement retained; absent pressure, temperature or phase conditions are not inferred.

  7. Hazardous Substances Data Bank (HSDB): Hexamethylenediamine — solubilityHazardous Substances Data Bank (HSDB)

    Retrieved through PubChem PUG View on 2026-09-08. https://pubchem.ncbi.nlm.nih.gov/compound/16402#section=Solubility. Source value, complete property clause or compact miscibility statement retained; absent pressure, temperature or phase conditions are not inferred. Original reference: Yalkowsky SH, Dannenfelser RM; The AQUASOL dATAbASE of Aqueous Solubility. Fifth ed, Tucson, AZ: Univ Az, College of Pharmacy (1992)