L-Leucine

L-Leucine is an organic compound with the molecular formula C6H13NO2.

Formula
C6H13NO2
Functional group
Amino acids
Molar mass
131.17 g/mol
Also known as
(2S)-2-amino-4-methylpentanoic acid, leucine, (S)-2-Amino-4-methylpentanoic acid, (S)-Leucine, (S)-(+)-Leucine, Leucin

Overview

L-Leucine is an organic compound with the molecular formula C6H13NO2.

Identifiers

Formula
C6H13NO2
Functional group
Amino acids
Molar mass
131.17 g/mol
Also known as
(2S)-2-amino-4-methylpentanoic acid, leucine, (S)-2-Amino-4-methylpentanoic acid, (S)-Leucine, (S)-(+)-Leucine, Leucin
Chemical identifiers
SMILES
CC(C)C[C@@H](C(=O)O)N
InChI
InChI=1S/C6H13NO2/c1-4(2)3-5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)/t5-/m0/s1
PubChem CID
6106

Properties

Melting Point
293 °C
Sublimation
Sublimes at 145-148 °C. Decomposes at 293-295 °C (rapid heating, sealed tube)
Density
1.293 g/cu cm at 18 °C
Water solubility
In water, 2.15X10+4 mg/L at 25 °C

Related compounds

References

  1. PubChem Compound Summary: L-Leucine (CID 6106)National Center for Biotechnology Information · PubChem

    Identity, molecular formula, molecular weight and aliases retrieved via PUG REST on 2026-09-08.

  2. Hazardous Substances Data Bank (HSDB): L-Leucine — melting pointHazardous Substances Data Bank (HSDB)

    Retrieved through PubChem PUG View on 2026-09-08. https://pubchem.ncbi.nlm.nih.gov/compound/6106#section=Melting-Point. Source value, complete property clause or compact miscibility statement retained; absent pressure, temperature or phase conditions are not inferred. Original reference: Lide, D.R. CRC Handbook of Chemistry and Physics 88TH Edition 2007-2008. CRC Press, Taylor & Francis, Boca Raton, FL 2007, p. 3-320

  3. Hazardous Substances Data Bank (HSDB): L-Leucine — boiling pointHazardous Substances Data Bank (HSDB)

    Retrieved through PubChem PUG View on 2026-09-08. https://pubchem.ncbi.nlm.nih.gov/compound/6106#section=Boiling-Point. Source value, complete property clause or compact miscibility statement retained; absent pressure, temperature or phase conditions are not inferred. Original reference: O'Neil, M.J. (ed.). The Merck Index - An Encyclopedia of Chemicals, Drugs, and Biologicals. Whitehouse Station, NJ: Merck and Co., Inc., 2006., p. 943

  4. Hazardous Substances Data Bank (HSDB): L-Leucine — densityHazardous Substances Data Bank (HSDB)

    Retrieved through PubChem PUG View on 2026-09-08. https://pubchem.ncbi.nlm.nih.gov/compound/6106#section=Density. Source value, complete property clause or compact miscibility statement retained; absent pressure, temperature or phase conditions are not inferred. Original reference: Lide, D.R. CRC Handbook of Chemistry and Physics 88TH Edition 2007-2008. CRC Press, Taylor & Francis, Boca Raton, FL 2007, p. 3-320

  5. Hazardous Substances Data Bank (HSDB): L-Leucine — solubilityHazardous Substances Data Bank (HSDB)

    Retrieved through PubChem PUG View on 2026-09-08. https://pubchem.ncbi.nlm.nih.gov/compound/6106#section=Solubility. Source value, complete property clause or compact miscibility statement retained; absent pressure, temperature or phase conditions are not inferred. Original reference: Yalkowsky, S.H., He, Yan., Handbook of Aqueous Solubility Data: An Extensive Compilation of Aqueous Solubility Data for Organic Compounds Extracted from the AQUASOL dATAbASE. CRC Press LLC, Boca Raton, FL. 2003., p. 316