N-substituted amides
N-substituted amides are formed by acylation of amines with acyl chlorides.
- Functional group
- CONHR / CONR2
- Also known as
- substituted amide, secondary amide, tertiary amide
Overview
Amide derivatives where nitrogen bears an organic substituent.
N-substituted amides are formed by acylation of amines with acyl chlorides.
Identifiers
- Functional group
- CONHR / CONR2
- Also known as
- substituted amide, secondary amide, tertiary amide
Chemical identifiers
- SMILES
- CC(=O)NC
Related compounds
- Acetanilide
An N-phenyl amide formed by acetylating aniline.
- Dimethylformamide
DMF, an N,N-disubstituted amide used as a polar aprotic solvent.
- Dimethylacetamide
Dimethylacetamide is an organic compound with the molecular formula C4H9NO.
- Paracetamol
Paracetamol is an organic compound with the molecular formula C8H9NO2.
Connected reactions
- Acylation: Acyl chlorides → N-substituted amides
Amine acylation converts acyl chlorides into N-substituted amides.
- Acylation co reactant: Amines → N-substituted amides
Amines are acylated by acyl chlorides to form N-substituted amides.
References
- PubChem Compound Summary: Acetanilide (CID 904)National Center for Biotechnology Information · PubChem
Identity, molecular formula, molecular weight and aliases retrieved via PUG REST on 2026-09-08.
- PubChem Compound Summary: Dimethylformamide (CID 6228)National Center for Biotechnology Information · PubChem
Identity, molecular formula, molecular weight and aliases retrieved via PUG REST on 2026-09-08.
- PubChem Compound Summary: Dimethylacetamide (CID 31374)National Center for Biotechnology Information · PubChem
Identity, molecular formula, molecular weight and aliases retrieved via PUG REST on 2026-09-08.
- PubChem Compound Summary: Paracetamol (CID 1983)National Center for Biotechnology Information · PubChem
Identity, molecular formula, molecular weight and aliases retrieved via PUG REST on 2026-09-08.