乙酸酐

乙酸酐，一种含两个相连乙酰基的酰化试剂。

化学式
C4H6O3
摩尔质量
102.09 g/mol
Also known as
acetyl acetate, Acetanhydride, Ethanoic anhydride, Acetyl oxide, Acetyl anhydride, Acetic oxide

概览

An oxygen atom joins two acyl groups. Reaction with an alcohol forms an ester and a carboxylic-acid coproduct; reaction with an amine can form an amide. It is more reactive toward these nucleophiles than a simple ester, but reaction conditions still control selectivity.

Identifiers

化学式
C4H6O3
摩尔质量
102.09 g/mol
Also known as
acetyl acetate, Acetanhydride, Ethanoic anhydride, Acetyl oxide, Acetyl anhydride, Acetic oxide
化学标识符
SMILES
CC(=O)OC(=O)C
InChI
InChI=1S/C4H6O3/c1-3(5)7-4(2)6/h1-2H3
PubChem CID
7918

性质

熔点
-73.4 °C
沸点
139.5 °C
密度
1.082 g/cu cm at 20 °C
水中溶解度
In water, 120 g/L at 20 °C

Related compounds

  • 酸酐

    Acetic anhydride is a specific member of the acid anhydrides family.

参考文献

  1. PubChem Compound Summary: Acetic anhydride (CID 7918)National Center for Biotechnology Information · PubChem

    Identity, molecular formula, molecular weight and aliases retrieved via PUG REST on 2026-09-08.

  2. OpenStax Organic Chemistry: Chemistry of acid anhydridesJohn McMurry · OpenStax · 2023

    Supports the qualitative structural interpretation of the recorded molecular structure; no new physical measurement or verified preparative yield is claimed.

  3. Hazardous Substances Data Bank (HSDB): Acetic anhydride — melting pointHazardous Substances Data Bank (HSDB)

    Retrieved through PubChem PUG View on 2026-09-08. https://pubchem.ncbi.nlm.nih.gov/compound/7918#section=Melting-Point. Source value, complete property clause or compact miscibility statement retained; absent pressure, temperature or phase conditions are not inferred. Original reference: Haynes, W.M. (ed.). CRC Handbook of Chemistry and Physics. 95th Edition. CRC Press LLC, Boca Raton: FL 2014-2015, p. 3-4

  4. Hazardous Substances Data Bank (HSDB): Acetic anhydride — boiling pointHazardous Substances Data Bank (HSDB)

    Retrieved through PubChem PUG View on 2026-09-08. https://pubchem.ncbi.nlm.nih.gov/compound/7918#section=Boiling-Point. Source value, complete property clause or compact miscibility statement retained; absent pressure, temperature or phase conditions are not inferred. Original reference: Haynes, W.M. (ed.). CRC Handbook of Chemistry and Physics. 95th Edition. CRC Press LLC, Boca Raton: FL 2014-2015, p. 3-4

  5. Hazardous Substances Data Bank (HSDB): Acetic anhydride — densityHazardous Substances Data Bank (HSDB)

    Retrieved through PubChem PUG View on 2026-09-08. https://pubchem.ncbi.nlm.nih.gov/compound/7918#section=Density. Source value, complete property clause or compact miscibility statement retained; absent pressure, temperature or phase conditions are not inferred. Original reference: Haynes, W.M. (ed.). CRC Handbook of Chemistry and Physics. 95th Edition. CRC Press LLC, Boca Raton: FL 2014-2015, p. 3-4

  6. Hazardous Substances Data Bank (HSDB): Acetic anhydride — solubilityHazardous Substances Data Bank (HSDB)

    Retrieved through PubChem PUG View on 2026-09-08. https://pubchem.ncbi.nlm.nih.gov/compound/7918#section=Solubility. Source value, complete property clause or compact miscibility statement retained; absent pressure, temperature or phase conditions are not inferred. Original reference: Yalkowsky, S.H., He, Yan, Jain, P. Handbook of Aqueous Solubility Data Second Edition. CRC Press, Boca Raton, FL 2010, p. 96