格氏试剂
格氏试剂的分子结构、物理性质与来源记录。查看化学标识、相关反应和材料用途。
- 官能团
- C-MgX
- Also known as
- organomagnesium halide, Grignard reagent
概览
Organomagnesium halides used for carbon-carbon bond formation.
Identifiers
- 官能团
- C-MgX
- Also known as
- organomagnesium halide, Grignard reagent
Connected reactions
- Grignard formation: Chloroalkanes → Grignard reagents
氯代烷可在无水乙醚中与镁反应，形成格氏试剂。
- Grignard formation: Bromoalkanes → Grignard reagents
溴代烷可在无水乙醚中与镁反应，形成格氏试剂。
- Grignard formation: Iodoalkanes → Grignard reagents
碘代烷可在无水乙醚中与镁反应，形成格氏试剂。
- Carbonyl addition: Grignard reagents → Primary alcohols
格氏试剂与甲醛加成，经后处理得到伯醇。
- Carbonyl addition: Grignard reagents → Secondary alcohols
格氏试剂与醛加成，经后处理得到仲醇。
- Carbonyl addition: Grignard reagents → Tertiary alcohols
格氏试剂与酮加成，经后处理得到叔醇。
- Carboxylation: Grignard reagents → Carboxylic acids
格氏羧化经酸性后处理得到羧酸。